VitalityCalculators
Last updated November 19, 2025

AST/ALT Ratio Calculator

Also known as:Liver Enzyme Ratio CalculatorTransaminase Ratio CalculatorDe Ritis Ratio CalculatorAST ALT Ratio Tool

Medically Reviewed

Dr. Jinlin Hou, MD

Board-Certified Gastroenterologist & Hepatologist, Southern Medical University China

·

Hepatology

Reviewed November 25, 2025

NIH — AST/ALT Ratio in Liver Disease Diagnosis

Disclaimer

The AST/ALT ratio provided by this calculator is intended for general informational and educational purposes only. It does not constitute medical advice, and a single ratio result should never be used to diagnose or rule out any liver condition. Liver enzyme levels can be influenced by medications, supplements, muscle injury, thyroid disorders, and laboratory-specific reference ranges. Always consult a qualified physician or gastroenterologist to interpret your liver function test results in the context of your full clinical picture.

Frequently Asked Questions

Everything you need to know about AST/ALT ratio and liver health

The AST/ALT Ratio Calculator measures the ratio of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) based on laboratory values. This ratio is primarily used to assess liver function and can provide insights into various liver diseases. A higher or lower ratio can indicate specific conditions such as alcoholic liver disease or non-alcoholic fatty liver disease.

To use the AST/ALT Ratio Calculator, you need to input the laboratory values for AST and ALT, which are usually reported in units per liter (U/L). Once you enter these values, the calculator will automatically compute the ratio for you. The result will help interpret potential liver conditions based on established medical guidelines.

The formula for calculating the AST/ALT ratio is straightforward: divide the value of AST by the value of ALT. For example, if your AST level is 80 U/L and your ALT level is 40 U/L, the ratio would be 2.0 (80/40). This ratio is then analyzed in the context of clinical criteria to determine possible liver conditions.

The results from the AST/ALT Ratio Calculator can provide valuable insights into potential liver health issues. Generally, a ratio greater than 2:1 suggests alcoholic liver disease, while a ratio less than 1 may indicate non-alcoholic fatty liver disease or viral hepatitis. However, results should always be interpreted in conjunction with other clinical information and tests.

Typically, a normal AST/ALT ratio falls between 0.7 and 1.0, indicating a balanced level of liver enzymes. Ratios above 1.0 can suggest liver disease, while a ratio below 0.7 may indicate other liver conditions. It's important to note that individual values can vary and should be interpreted by a healthcare professional.

The AST/ALT Ratio Calculator has limitations, as the ratio alone cannot definitively diagnose liver conditions. Factors like age, sex, and muscle mass can influence AST and ALT levels. Additionally, other tests and clinical evaluations are necessary to confirm any diagnosis suggested by the ratio.

The AST/ALT Ratio Calculator is beneficial for individuals who have undergone liver function tests and want to understand their results better. It is particularly useful for patients at risk of liver disease, including those with a history of alcohol use, obesity, or viral hepatitis. However, it is essential to consult a healthcare provider for comprehensive diagnosis and treatment.

The AST/ALT Ratio Calculator can be used whenever you receive new AST and ALT liver enzyme results from your healthcare provider. It's advisable to check the ratio after any significant changes in health, lifestyle, or treatment plans related to liver health. Regular monitoring may be necessary if you are at risk for liver disease.

You should consider consulting a doctor if the AST/ALT ratio indicates potential liver disease, such as a ratio greater than 2.0 or significant deviations from the normal range. If you experience symptoms like jaundice, abdominal pain, or unexplained fatigue, seeking medical advice promptly is crucial. A healthcare professional can provide further testing and appropriate management.

When interpreting the AST/ALT ratio, it's important to consider other factors such as the patient's medical history, medication use, and lifestyle factors like alcohol consumption. Some conditions, such as muscle disorders, can elevate AST levels independently of liver health, potentially skewing the ratio. Thus, a holistic view of a patient's health is necessary for accurate interpretation.

Yes, the AST/ALT Ratio Calculator can provide clues about the type of liver disease based on the resulting ratio. For instance, a ratio greater than 2 is often associated with alcoholic liver disease, while a ratio less than 1 may suggest non-alcoholic fatty liver disease. However, it is critical to combine this data with other diagnostic information for a comprehensive assessment.

The AST/ALT ratio is a valuable indicator for monitoring liver health, as changes in this ratio can signal the progression or improvement of liver conditions. Regular assessments using this calculator can help track liver enzyme levels over time. This ongoing monitoring is particularly important for individuals with pre-existing liver conditions or risk factors.

While the AST/ALT ratio calculator is primarily focused on liver health, it can serve as a useful tool in broader health assessments, especially for individuals at risk of liver disease. Elevated liver enzymes can indicate underlying health issues that may require further investigation. However, it should not replace comprehensive medical evaluations or routine health screenings.

If your AST/ALT ratio is abnormal, it's vital to follow up with your healthcare provider for further evaluation. They may recommend additional tests, lifestyle changes, or treatment options based on the underlying cause of the abnormality. Avoiding self-diagnosis and relying on professional guidance is essential for effective management of liver health.

Yes, lifestyle changes can significantly impact your AST/ALT ratio. Reducing alcohol consumption, maintaining a healthy weight, and following a balanced diet can help improve liver enzyme levels. Regular exercise also plays a crucial role in liver health, potentially leading to a more favorable AST/ALT ratio.

AST/ALT Ratio Calculator

Calculate your liver enzyme ratio and assess hepatic health

Reference Ranges

AST (normal)
10 – 40 U/LMen & Women
ALT (normal)
7 – 56 U/LMen & Women
Ratio < 1.0
ALT-dominantViral hepatitis / NAFLD
Ratio 1.0 – 2.0
BorderlineMixed or borderline
Ratio ≥ 2.0
AST-dominantAlcoholic liver disease

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