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The CHA₂DS₂-VASc Score Calculator is a clinical tool used to estimate stroke risk in patients with atrial fibrillation (AFib). It assigns points for specific risk factors (congestive heart failure, hypertension, age, diabetes, stroke history, vascular disease, and sex) to determine the need for anticoagulation therapy.
The calculator assigns points as follows:
Congestive heart failure: 1 point
Hypertension: 1 point
A₂ge ≥75: 2 points
Diabetes: 1 point
S₂troke/TIA history: 2 points
Vascular disease: 1 point
Age 65-74: 1 point
Sc (female sex): 1 point
The total score correlates with annual stroke risk and guides anticoagulation decisions.
This score helps clinicians stratify stroke risk in AFib patients and make evidence-based decisions about anticoagulation therapy, balancing stroke prevention against bleeding risks.
Score 0 (men) or 1 (women): Low risk (~0-1.3% annual stroke risk)
Score 1 (men): Moderate risk (~1.3-2.2%)
Score ≥2 (men) or ≥3 (women): High risk (~2.2-15.2%)
The calculator has good predictive accuracy (c-statistic ~0.6-0.7), though individual factors like labile INRs or extreme ages may affect precision. It’s validated in multiple international guidelines.
Female sex adds 1 point due to studies showing women with AFib have slightly higher stroke risks than men after adjusting for other factors. However, sex alone shouldn’t dictate treatment.
Age is categorized:
65-74 years = 1 point
≥75 years = 2 points
These aren’t additive – a 78-year-old would only get 2 points, not 3 (1 for 65-74 + 2 for ≥75).
Vascular disease includes:
Prior myocardial infarction
Peripheral artery disease
Aortic plaque
Carotid artery disease
Recalculate annually or when:
New risk factors emerge
After stroke/TIA events
When considering anticoagulation changes
Score 0 (men)/1 (women): No anticoagulation typically needed
Score 1 (men): Consider anticoagulation based on bleeding risk
Score ≥2 (men)/≥3 (women): Anticoagulation recommended in most cases
No. The score informs but doesn’t replace judgment. Factors like bleeding risk, patient preferences, and fall risk must also be considered when prescribing anticoagulants.
It doesn’t account for:
Bleeding risk (use HAS-BLED concurrently)
AFib burden (paroxysmal vs persistent)
Some stroke risk modifiers (e.g., CKD, OSA)
Derived from large cohort studies (n>10,000) and validated in multiple populations. Incorporated in major guidelines (AHA/ACC, ESC).
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